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Diffusion-based hierarchical multi-label object detection to analyze panoramic dental X-rays
Hamamcı, İbrahim Ethem; Er, Sezgin; Simsar, Enis; Sekuboyina, Anjany; Gündoğar, Mustafa; Stadlinger, Bernd; Mehl, Albert; Menze, Bjoern (Springer Science and Business Media Deutschland GmbH, 2023)Due to the necessity for precise treatment planning, the use of panoramic X-rays to identify different dental diseases has tremendously increased. Although numerous ML models have been developed for the interpretation of ... -
A novel theanine complex, Mg-L-Theanine improves sleep quality via regulating brain electrochemical activity
Daşdelen, Muhammed Furkan; Er, Sezgin; Kaplan, Berkan; Çelik, Süleyman; Beker, Mustafa Çağlar; Orhan, Cemal; Tuzcu, Mehmet; Şahin, Nurhan; Mamedova, Havakhanum; Sylla, Sarah; Komorowski, James; Ojalvo, Sara Perez (Frontiers Media S.A., 2022)L-Theanine is commonly used to improve sleep quality through inhibitory neurotransmitters. On the other hand, Mg2+, a natural NMDA antagonist and GABA agonist, has a critical role in sleep regulation. Using the caffeine-induced ... -
Social isolation initiated post-weaning augments ischemic brain injury by promoting pro-inflammatory responses
Daşdelen, Muhammed Furkan; Çağlayan, Ahmet Burak; Er, Sezgin; Beker, Mustafa Çağlar; Ateş, Nilay; Gronewold, Janine; Doeppner, Thorsten Roland; Hermann, Dirk M.; Kılıç, Ertuğrul (Academic Press Inc., 2024)Social isolation is associated with poor stroke outcome, but the underlying molecular mechanisms were largely unknown. In male Balb/C mice exposed to transient middle cerebral artery occlusion (MCAo), we examined the effects ... -
Two phases of macrophages: Inducing maturation and death of oligodendrocytes in vitro co-culture
Aydınlı, Fatmagül İlayda; Er, Sezgin; Kerman, Bilal Ersen (Elsevier B.V., 2022)Background: The plasticity of macrophages in the immune response is a dynamic situation dependent on external stimuli. The activation of macrophages both has beneficial and detrimental effects on mature oligodendrocytes ...